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Tocris Bioscience™ Lonafarnib
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Artikelnummer. 18748236
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10 mg
50 mg
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10mg
50mg
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18748236 10 mg 10mg
18799046 50 mg 50mg
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Artikelnummer. 18748236 Leverandør Tocris Bioscience™ Leverandørnr. 6265/10
  • ONLINE EXCLUSIVE PRICE
    € 222.00
    € 210.00 / 10mg
    Save € 12.00
    5% Off
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Estimated Shipment: 07-08-2026
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Beskrivelse

Potent farnesyl transferase inhibitor

Lonafarnib is a potent farnesyl transferase inhibitor (IC50 = 1.9 nM). Inhibits farnesylation of RAS. Also inhibits Pgp transport (IC50 < 3 μM) and increases potency and anticancer activity when used in conjunction with cytotoxic Pgp substrates. Inhibits neovascularization by affecting cell motility. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Tekniske data

Chemical Name or Material 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide
CAS 193275-84-2
Assay Percent Range >98%
Quantity 10 mg
Molecular Formula C27H31Br2ClN4O2
Formula Weight Observed MW: 638.82
Produkttitel
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