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Invitrogen™ LOX-1 Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA547158
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Description
This antibody can block receptor-ligand interaction in a functional ELISA assay. In Western blots, approximately 5% cross-reactivity with recombinant human LOX-1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 μg of the antibody by the LAL method.
LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.
Specifications
| LOX-1 | |
| Polyclonal | |
| Unconjugated | |
| OLR1 | |
| CLEC8A; C-type lectin domain family 8 member A; hLOX 1; hLOX1; hLOX-1; lectin-like oxidized LDL receptor; lectin-like oxidized LDL receptor 1; lectin-like oxidized low-density lipoprotein receptor; Lectin-like oxidized low-density lipoprotein receptor-1; lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX 1; LOX1; LOX-1; LOXIN; Oldlr1; Oldr1; OLR1; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; ox-LDL receptor 1; Scare1; scavenger receptor class E, member 1; sLOX 1; SLOX1; soluble LOX 1; SR-EI | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 108078 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Neutralization, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| Q9EQ09 | |
| OLR1 | |
| Mouse myeloma cell line NS0-derived recombinant mouse LOX-1 Arg60-Ile363. | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG |
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