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Invitrogen™ LOX Recombinant Rabbit Monoclonal Antibody (9K10Z3)
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Product Code. 17185783
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Quantity:
100 μL
Unit Size:
100µL
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17185783 100 μL 100µL
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Product Code. 17185783 Supplier Invitrogen™ Supplier No. MA535123

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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: GHKASFCLED TSCDYGYHRR FACTAHTQGL SPGCYDTYGA DIDCQWIDIT DVKPGNYILK VSVNPSYLVP ESDYTNNVVR CDIRYTGHHA YASGCTISPY.

Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. It plays a vital role in the formation and repair of the extra cellular matrix. As well, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, it is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LOX
Applications ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone 9K10Z3
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene LOX
Gene Accession No. P16636, P28300, P28301
Gene Alias AI893619; cross-linking enzyme; H-rev142; LOX; Lysyl oxidase; Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts); MGC105112; protein-lysine 6-oxidase; Protein-lysine 6-oxidase, long form; Protein-lysine 6-oxidase, short form; Ras excision protein; ras recision; rrg; Rrg1; TSC-160
Gene Symbols LOX
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 318-417 of human LOX (P28300).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16948, 24914, 4015
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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