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Invitrogen™ LOXL3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA545074
This item is not returnable.
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Description
Peptide sequence: AASSGQKKQQ QSKPQGEARV RLKGGAHPGE GRVEVLKAST WGTVCDRKWD Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 93%; Rat: 93%.
LOXL3 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Specifications
| LOXL3 | |
| Polyclonal | |
| Unconjugated | |
| LOXL3 | |
| Lor2; LOW QUALITY PROTEIN: lysyl oxidase homolog 3; LOXL; Loxl2; Loxl3; Lysyl oxidase homolog 3; lysyl oxidase like 3; lysyl oxidase-like 2; lysyl oxidase-like 3; lysyl oxidase-like protein 3; Lysyl oxidase-related protein 2 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 84695 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 2% sucrose and 0.09% sodium azide | |
| P58215 | |
| LOXL3 | |
| Synthetic peptide directed towards the middle region of human LOXL3. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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