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Invitrogen™ LRGUK Polyclonal Antibody
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Product Code. 15714091 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15714091 100 μL 100µL
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Product Code. 15714091 Supplier Invitrogen™ Supplier No. PA556175

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SNMGDFLHST DRNYLIKFWA KLSAKKTPAE RDSIHRQHEA ARQALMGRIR PDHTLLFQRG PVPAPLTSGL HYYTTLEELW KSFDLCEDYF KPPFG Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 61%.

The LRGUK (Leucine-Rich Repeat and Guanylate Kinase-Like Domain Containing 1) gene encodes a protein that plays a critical role in male fertility. It is particularly important for the proper function of the manchette, a microtubule-based structure involved in sperm head shaping and tail formation during spermiogenesis. Research has shown that LRGUK1 is part of a multiprotein complex essential for the initiation of sperm tail growth from the centriole/basal body. Mutations or disruptions in the LRGUK1 gene can lead to defective manchette function, resulting in abnormal sperm morphology and infertility. This gene's role in spermatogenesis underscores its importance in reproductive health, with ongoing studies aimed at elucidating its specific interactions and mechanisms within the manchette complex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen LRGUK
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene LRGUK
Gene Accession No. Q96M69
Gene Alias 4921528H16Rik; CFAP246; leucine rich repeats and guanylate kinase domain containing; leucine-rich repeat and guanylate kinase domain-containing protein; leucine-rich repeats and guanylate kinase domain containing; Lrguk; RGD1308226
Gene Symbols LRGUK
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human LRGUK. Recombinant protein control fragment (Product #RP-92765).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 136332
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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