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Invitrogen™ LRRC19 Polyclonal Antibody

Description
LRRC19 Polyclonal Antibody for IHC (P)
LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappa-B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
Spécification
Spécification
| Antigen | LRRC19 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 100 μg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.03% ProClin 300; pH 7 |
| Gene | LRRC19 |
| Gene Accession No. | Q9H756 |
| Gene Alias | 9130022A01Rik; AI314124; AL022954; AW261791; leucine rich repeat containing 19; leucine-rich repeat-containing protein 19; LRRC19 |
| Gene Symbols | LRRC19 |
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Nom du produit
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