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Ly-49G2 Monoclonal Antibody (eBio4D11 (4D11)), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

€ 114.00 - € 390.00

Specifications

Antigen Ly-49G2
Clone eBio4D11 (4D11)
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15331350
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Affymetrix eBioscience
46-5781-82
100 μg
€ 390.00
100µg
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15321350
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Affymetrix eBioscience
46-5781-80
25 μg This item is currently unavailable or has been discontinued.
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Description

Description

Description: The 4D11 monoclonal antibody reacts with Ly-49G2 (also known as LGL-1). The Ly-49 family of NK-cell receptors, members of the C-type lectin superfamily, are disulfide-linked type-II transmembrane protein homodimers with extracellular carbohydrate recognition domains, which bind to MHC class I alloantigens. The Ly-49 family members are expressed independently, such that an individual NK or T cell may display more than one class of Ly-49 receptor. Ly-49G2 is an inhibitory receptor expressed on subsets of natural killer (NK) cells, NK-T cells (in all strains tested), and on a population of memory CD8+ T cells (in C57BL/6 mice). The 4D11 antibody has been reported to cross react with the Ly-49AB6, Ly-49ABALB, and Ly-49T129/J inhibitory receptors and Ly-49LCBA/J activatingreceptors. The proportion of NK-T cells expressing Ly-49A and Ly-49G2 is higher in the thymus than in liver, and there is evidence that down-regulation of Ly-49 receptor expression is necessary for normal NK-T-cell development to occur. Applications Reported: This eBio4D11 (4D11) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio4D11 (4D11) antibody has been tested by flow cytometric analysis of mouse spleen cells. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.

Ly-49G2 Monoclonal antibody specifically detects Ly-49G2 in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

Ly-49G2
0.2 mg/mL
Monoclonal
Liquid
RUO
Q60654
Klra7
Primary
4° C, store in dark, DO NOT FREEZE!
Klra7
eBio4D11 (4D11)
Flow Cytometry
PerCP-eFluor 710
Rat
Mouse
16638
IgG2a κ
Affinity chromatography
Antibody
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