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Invitrogen™ Ly-6E Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5120075
This item is not returnable.
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Description
Positive test controls include: LO2, 293T, SKOV3, MCF7, U-87MG, Mouse brain, Mouse kidney, Mouse liver. The target is usually found in the following locations: Cell membrane, GPI-anchor, Lipid-anchor. Immunogen sequence: LMCFSCLNQK SNLYCLKPTI CSDQDNYCVT VSASAGIGNL VTFGHSLSKT CSPACPIPEG VNVGVASMGI SCCQSFLCNF S.
Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.
Specifications
| Ly-6E | |
| Polyclonal | |
| Unconjugated | |
| LY6E | |
| 9804; locus A/E; Locus AE; Ly67; Ly6A; Ly6e; ly-6E; lymphocyte antigen 6 complex, locus E; lymphocyte antigen 6E; retinoic acid induced gene E; retinoic acid-induced gene E protein; RIGE; RIG-E; SCA2; SCA-2; Stem cell antigen 2; thymic shared antigen 1; Tsa1; Tsa-1 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 17069, 362934 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot, Immunocytochemistry | |
| 0.53 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 | |
| Q64253 | |
| LY6E | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 21-101 of human LY6E (NP_002337.1). | |
| 100 μL | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
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