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Invitrogen™ LYAG Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA582947
This item is not returnable.
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Description
Immunogen sequence: SSEMGYTATL TRTTPTFFPK DILTLRLDVM METENRLHFT IKDPANRRYE VPLETPHVHS RAPSPLYSVE FSEEPFGVIV RRQLDGRVLL NTTVAPLFFA DQFLQLSTS Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 84%.
This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.
Specifications
| LYAG | |
| Polyclonal | |
| Unconjugated | |
| Gaa | |
| 70 kDa lysosomal alpha-glucosidase; 76 kDa lysosomal alpha-glucosidase; acid (Pompe disease, glycogen storage disease type II); acid alpha-glucosidase; acid maltase; Aglucosidase alfa; E430018M07Rik; Gaa; glucosidase alpha, acid; glucosidase, alpha, acid; glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II); LYAG; Lysosomal alpha-glucosidase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 2548 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P10253 | |
| Gaa | |
| Recombinant protein corresponding to Human GAA. Recombinant protein control fragment (Product #RP-90468). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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