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Invitrogen™ LYK5 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA528594

Product Code. 13492707

  • € 514.00 / 100µL

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Description

Description

Recommended positive controls: 293T, HepG2, mouse brain. Predicted reactivity: Human (98%), Mouse (95%), Rat (94%), Chicken (90%), Sheep (95%), Chimpanzee (98%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

LYK5; STE20-related Adaptor Protein (STRAD); FLJ90524. Gene Map Locus is 17q23.3 and members of STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. STRAD is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction results in phosphorylation of STRAD and enhanced autophosphorylation of LKB1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

LYK5
Polyclonal
Unconjugated
STRADA
2610019A05Rik; 6030402H20Rik; AI480680; E130112C09Rik; LYK5; NY-BR-96; PMSE; protein kinase LYK5; serologically defined breast cancer antigen NY-BR-96; STE20-like pseudokinase; STE20-related adapter protein; STE20-related kinase adapter protein alpha; STE20-related kinase adaptor alpha; Stlk; Strad; STRAD alpha; Strada
Rabbit
Antigen affinity chromatography
RUO
72149, 92335
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Q3UUJ4, Q7RTN6
STRADA
Recombinant protein encompassing a sequence within the center region of human LYK5. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse
Antibody
IgG
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