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Invitrogen™ Lyn Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA527361
This item is not returnable.
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Description
Recommended positive controls: HeLa, CD44-knockout HeLa, Raji, K562, THP-1. Predicted reactivity: Mouse (94%), Rat (95%), Xenopus laevis (83%), Sheep (87%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
Specifications
| Lyn | |
| Polyclonal | |
| Unconjugated | |
| LYN | |
| AA407514; CD180; CD180 antigen; CD180 molecule; CH73-38P6.3; FLJ26625; Hck-2; JTK8; lck/Yes-related novel protein tyrosine kinase; LY64; Ly78; lymphocyte antigen 64; lymphocyte antigen-64, radioprotective, 105kDa; LYN; lyn protein non-receptor kinase; lyn protein tyrosine kinase; LYN proto-oncogene, Src family tyrosine kinase; p53Lyn; p56Lyn; Radioprotective 105 kDa protein; RP105; Tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog; zgc:92124 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 17096, 4067, 81515 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| P07948, P25911, Q07014 | |
| LYN | |
| Recombinant protein encompassing a sequence within the center region of human LYN. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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