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Invitrogen™ Lyn Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5119830
This item is not returnable.
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Description
Positive Control: 293T cell lysate, A431 cell lysate, mouse liver tissue lysate, rat brain tissue lysates. Subcellular Location: Cell membrane, Cytoplasm, Golgi apparatus, Membrane, Nucleus.
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
Specifications
| Lyn | |
| Polyclonal | |
| Unconjugated | |
| LYN | |
| AA407514; CD180; CD180 antigen; CD180 molecule; CH73-38P6.3; FLJ26625; Hck-2; JTK8; lck/Yes-related novel protein tyrosine kinase; LY64; Ly78; lymphocyte antigen 64; lymphocyte antigen-64, radioprotective, 105kDa; LYN; lyn protein non-receptor kinase; lyn protein tyrosine kinase; LYN proto-oncogene, Src family tyrosine kinase; p53Lyn; p56Lyn; Radioprotective 105 kDa protein; RP105; Tyrosine-protein kinase Lyn; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein; Yamaguchi sarcoma viral (v-yes-1) oncogene homolog; zgc:92124 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 17096, 4067, 81515 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4 | |
| P07948, P25911, Q07014 | |
| LYN | |
| Recombinant protein within human Lyn aa 1-200. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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