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Invitrogen™ MALSU1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA562569
This item is not returnable.
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Description
Immunogen sequence: GSAVGAEPGL RLLAVQRLPV GAAFCRACQT PNFVRGLHSE PGLEERAEGT VNEGRPESDA ADHTGPKFDI DMMVSLLRQE NARDICVIQV PPEMRYTDYF VIVS Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 59%.
Required for normal mitochondrial ribosome function and mitochondrial translation (PubMed:22238375, PubMed:23171548). May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S ribosomal subunits and the formation of functional ribosomes (Probable). May also participate in the assembly and/or regulation of the stability of the large subunit of the mitochondrial ribosome (PubMed:22238376, PubMed:23171548). May function as a ribosomal silencing factor (Probable). [UniProt].
Specifications
| MALSU1 | |
| Polyclonal | |
| Unconjugated | |
| MALSU1 | |
| 2410003K15Rik; C7orf30; Malsu1; Matsu1; mitochondrial assembly of ribosomal large subunit 1; mitochondrial assembly of ribosomal large subunit protein 1; mtRsfA; protein C7orf30 homolog; RGD1306936 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 115416 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.5 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q96EH3 | |
| MALSU1 | |
| Recombinant protein corresponding to Human MALSU1. Recombinant protein control fragment (Product #RP-92768). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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