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MAP2K1 Monoclonal Antibody (OTI1E5), TrueMAB™, OriGene
Description
MEK1 (mitogen activated protein kinase kinase, ERK kinase 1, microtubule-associated protein 2 kinase) is a dual specificity kinase and catalyses both a threonine and a tyrosine residue on MAP kinases ERK1 and ERK2. Mek1 is activated by phosphorylation of serine 218 and 222 residues by Raf1. It is known to be involved in the signaling during stress activate response, apoptosis and proliferative induction by cytokines. Mutations in MEK1 can lead to cardiofaciocutaneous syndrome.
Specifications
Specifications
| Antigen | MAP2K1 |
| Applications | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | OTI1E5 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 50% glycerol and 0.02% sodium azide |
| Gene | MAP2K1 |
| Gene Accession No. | P31938, Q01986, Q02750 |
| Gene Alias | CFC3, MAPKK1, MEK1, MKK1, PRKMK1 |
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Product Title
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