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Invitrogen™ Human MAP2K4 (MEK4), GST Tag Recombinant Protein
Human MAP2K4 (MEK4), GST Tag Recombinant Protein
€ 520.00 - € 7580.00
Specifications
| Accession Number | NP_003001 |
|---|---|
| For Use With (Application) | Kinase Assay |
| Molecular Weight (g/mol) | 70.6 kDa |
| KinaseFamily | MAP Kinases |
| Protein Length | Full Length |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17178745
|
Invitrogen™
A32894 |
100 mg |
€ 2435.00
100µg |
Estimated Shipment: 29-05-2024 Log in to see stock. |
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|
15940303
|
Invitrogen™
A30976 |
10 mg |
€ 520.00
10µg |
Estimated Shipment: 08-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
|
17138795
|
Invitrogen™
A33379 |
1 mg |
€ 7580.00
1mg |
Estimated Shipment: 28-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38. MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs. MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines. MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors. Conversely, a pro-oncogenic role was also found for MAP2K4.- Validated for use with the LanthaScreen™ Eu Kinase Binding assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_003001 | |
| 70.6 kDa | |
| Full Length | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Full Length, Recombinant, Active |
| Kinase Assay | |
| MAP Kinases | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Liquid |