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Invitrogen™ MAPKAPK5 Polyclonal Antibody
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Product Code. 16693575
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Quantity:
100 μL
Unit Size:
100µL
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16693575 100 μL 100µL
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Product Code. 16693575 Supplier Invitrogen™ Supplier No. PA599329

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MAPKAPK5.

MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAPKAPK5
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAPKAPK5
Gene Accession No. O54992, Q8IW41
Gene Alias MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK
Gene Symbols MAPKAPK5
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAPKAPK5(Accession Q8IW41), corresponding to amino acid residues G328-D378.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17165, 8550
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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