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Invitrogen™ MASTL Polyclonal Antibody
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Product Code. 16322255
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16322255 100 μL 100µL
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Product Code. 16322255 Supplier Invitrogen™ Supplier No. PA585313

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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (80%), Rat (81%), Bovine (88%). Positive Control: 293T, A431, HeLa, HepG2, MASTL-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

MASTL or microtubule associated serine/threonine kinase-like belongs to the MAST family, AGC Ser/Thr protein kinase group. MASTL promotes mitotic progression and cell cycle reentry after DNA damage. Loss of MASTL leads to defects in chromosome condensation, separation, and other aspects of mitotic progression, which is primarily mediated by inhibiting PP2A/B55 delta. Overexpression of MASTL is correlated with cancer progression, poor patient survival, and tumor recurrence in various cancers. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MASTL
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene MASTL
Gene Accession No. Q96GX5
Gene Alias 2700091H24Rik; C88295; GREATWALL; greatwall kinase homolog; greatwall protein kinase; GW; GWL; hGWL; Mastl; MAST-L; microtubule associated serine/threonine kinase like; microtubule associated serine/threonine kinase-like; microtubule-associated serine/threonine-protein kinase-like; RP11-85G18.2; Serine/threonine-protein kinase greatwall; THC2
Gene Symbols MASTL
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MASTL. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84930
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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