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Invitrogen™ MAX Polyclonal Antibody

Description
Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS. Predicted reactivity: Mouse (99%), Rat (93%), Zebrafish (83%), Xenopus laevis (87%), Cat (93%), Rhesus Monkey (100%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature for some of them is unknown.
Specifications
Specifications
| Antigen | MAX |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Concentration | 1.23 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.025% ProClin 300; pH 7 |
| Gene | MAX |
| Gene Accession No. | P61244 |
| Gene Alias | AA960152; AI875693; bHLHd4; bHLHd5; bHLHd6; bHLHd7; bHLHd8; Class D basic helix-loop-helix protein 4; Delta-Max; Max; Max protein; MGC10775; MGC11225; MGC18164; MGC34679; MGC36767; MYC associated factor X; myc-associated factor X; Myc-binding novel HLH/LZ protein; Myn; orf1; Protein max; protein myn |
| Gene Symbols | MAX |
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