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Tocris Bioscience™ MB 05032
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Product Code. 18776796
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18776796 50 mg 50mg
18748856 10 mg 10mg
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Product Code. 18776796 Supplier Tocris Bioscience™ Supplier No. 6618/50

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Description

Potent FBPase inhibitor; promotes HSC expansion

MB 05032 is a potent FBPase inhibitor (EC50 values are 1.6, 29 and 61 nM for human liver FBPase, human muscle FBPase and rat liver FBPase). Promotes hematopoietic stem cell and progenitor cell expansion. Increases engraftment in primary NSG mice recipients. Also enhances myeloid and lymphoid chimerism in secondary NSG mouse recipients. Promotes glycolysis, glucose uptake and lactate production in umbilical cord blood CD34+ cells.
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Specifications

Chemical Name or Material P-[5-[2-Amino-5-(2-methylpropyl)-4-thiazolyl]-2-furanyl]phosphonic acid
CAS 261365-11-1
Quantity 50 mg
Molecular Formula C11H15N2O4PS
Formula Weight 302.29
Purity 98%
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