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Invitrogen™ MCFD2 Polyclonal Antibody

Description
Reconstitute at 0.2 mg/mL in sterile PBS.
Multiple coagulation factor deficiency protein 2 (MCFD2) is localized in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) through a direct, calcium-dependent interaction with LMAN1. The MCFD2-LMAN1 complex forms a specific cargo receptor for the transport of selected proteins from the endoplasmic reticulum to the Golgi apparatus. Mutations in the MCFD2 gene may cause of factor V and factor VIII combined deficiency (F5F8D). F5F8D is an autosomal recessive human bleeding disorder characterized by the reduction of both clotting proteins.
Specifications
Specifications
| Antigen | MCFD2 |
| Applications | Immunohistochemistry (Frozen), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 5% trehalose and No Preservative |
| Gene | Mcfd2 |
| Gene Accession No. | Q8K5B2 |
| Gene Alias | 1810021C21Rik; F5F8D; F5F8D2; LMAN1IP; MCFD2; multiple coagulation factor deficiency 2; multiple coagulation factor deficiency protein 2; Multiple coagulation factor deficiency protein 2 homolog; neural stem cell derived neuronal survival protein; neural stem cell-derived neuronal survival protein; Sdnsf; stem cell derived neuronal survival protein |
| Gene Symbols | Mcfd2 |
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