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MCM6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16881504 Shop All Proteintech Products
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150 μL
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16881504 20 μL 20µL
16871504 150 μL 150µL
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Product Code. 16881504 Supplier Proteintech Supplier No. 133472AP20UL

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Rabbit Polyclonal Antibody

The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.

Specifications

Antigen MCM6
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MCM6
Gene Accession No. P97311, Q14566, Q62724
Gene Alias MCG40308, MCM6, Mis5, P105MCM
Gene Symbols Mcm6
Host Species Rabbit
Immunogen MCM6 Fusion Protein Ag4180
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17219, 29685, 4175
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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