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Invitrogen™ MDFI Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5142482
This item is not returnable.
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.
Specifications
| MDFI | |
| Polyclonal | |
| Unconjugated | |
| Mdfi | |
| I-mf; I-mfa; inhibitor of MyoD family a; MDFI; MyoD family inhibitor; myogenic repressor I-mf; RGD1560271 | |
| Goat | |
| Ammonium Sulfate Precipitation | |
| RUO | |
| 4188 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q99750 | |
| Mdfi | |
| Peptide with sequence C-SKSTTSQIPLQAQED (aa 148-162). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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