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Invitrogen™ MED6 Polyclonal Antibody

Description
Peptide sequence: LLLDLRQKFP PKFVQLKPGE KPVPVDQTKK EAEPIPETVK PEEKETTKNV Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 93%.
MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Specifications
Specifications
| Antigen | MED6 |
| Applications | ChIP Assay, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 2% sucrose and 0.09% sodium azide |
| Gene | Med6 |
| Gene Accession No. | O75586 |
| Gene Alias | 1500012F11Rik; Activator-recruited cofactor 33 kDa component; ARC33; AU019660; AV213303; CTD-2540L5.5; hMed6; hypothetical protein LOC505293; MED6; Mediator complex subunit 6; mediator of RNA polymerase II transcriptio subunit 6-like protein; mediator of RNA polymerase II transcription subunit 6; mediator of RNA polymerase II transcription, subunit 6 homolog; NY-REN-28; Renal carcinoma antigen NY-REN-28 |
| Gene Symbols | Med6 |
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