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Invitrogen™ MEK2 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA587392

Product Code. 16525891

  • € 520.00 / 100µL

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Description

Description

Positive Samples: Mouse brain; Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein Immunogen sequence: MLARRKPVLP ALTINPTIAE GPSPTSEGAS EANLVDLQKK LEELELDEQQ KKRLEAFLTQ KAKVGELKDD DFERISELGA GNGGVVTKVQ HRPSGLIMAR.

MAP2K2 (MEK2) is a dual specificity serine/threonine kinase that is known to play a critical role in mitogen growth factor signal transduction. Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MEK2
Polyclonal
Unconjugated
MAP2K2
AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45
Rabbit
Affinity chromatography
RUO
26396
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
0.81 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q63932
MAP2K2
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEK2 (NP_1095871).
100 μL
Primary
Mouse, Rat
Antibody
IgG
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