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Description
Immunogen sequence: IPASMNYAKA HSKDKKKPQR DSQAQKSPVK SKSTHRIQHN IDYLKHLSKV KKIPSDFEGS GYTDLQERGD NDISPFSGDG QPFKDIPGKG EATGPD Highest antigen sequence identity to the following orthologs: Mouse - 53%, Rat - 48%.
Matrix extracellular phosphoglycoprotein (MEPE), also known as osteoblast/osteocyte factor 45 (OF45), is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family. MEPE promotes renal phosphate excretion and modulates mineralization. It can be phosphorylated by secreted protein kinases. MEPE is expressed in osteoblasts, osteocytes and odontoblasts, and the expression has also been reported in numerous human tumor cell lines. It is a 525-amino acid protein with a calculated molecular weight of 58 kDa.
Specifications
Specifications
| Antigen | MEPE |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.4 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | MEPE |
| Gene Accession No. | Q9NQ76 |
| Gene Alias | Matrix extracellular phosphoglycoprotein; matrix extracellular phosphoglycoprotein with ASARM motif (bone); matrix, extracellular phosphoglycoprotein with ASARM motif (bone); Mepe; OF45; osteoblast/osteocyte factor 45; Osteoregulin |
| Gene Symbols | MEPE |
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