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Invitrogen™ mGluR2/mGluR3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA146113
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Description
This antibody is predicted react to human and mouse based on sequence homology.
The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
Specifications
| mGluR2/mGluR3 | |
| Polyclonal | |
| Unconjugated | |
| Grm2 | |
| 0710001G23Rik; 4930441L02Rik; G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member C; GLUR2; GLUR3; glutamate metabotropic receptor 2; glutamate metabotropic receptor 3; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; glutamate receptor, metabotropic 3; Gprc1b; GPRC1C; GRM2; Grm3; M mGlu3; Metabotropic glutamate receptor 2; metabotropic glutamate receptor 3; mGlu2; mGlu3; mGluR2; MGLUR3; mGluR7 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 24415, 24416 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| P31421, P31422 | |
| Grm2, Grm3 | |
| Synthetic peptide corresponding to residues 860-875 of the rat mGlurR2/3 protein. | |
| 100 μg | |
| Primary | |
| Rat | |
| Antibody | |
| IgG |
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