MHC Class II (I-A/I-E), APC-eFluor 780, clone: M5/114.15.2, eBioscience™
Rat Monoclonal Antibody
Merk: Affymetrix eBioscience 47-5321-80
Overige gegevens : Gewicht : 0.25000kg
BeschrijvingPlease protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (cat. 00-8222) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (cat. 00-5333) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 633-647 nm; Emission: 780 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
|MHC Class II (I-A/I-E)|
|PBS with 0.09% sodium azide; pH 7.2|
|I-Ab, I-Ad, I-Aq, I-Ed, I-Ek, MHC class 2, MHC class II glygoproteins|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.