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MI-136, MedChemExpress

Product Code. 16467586
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Product Code. 16467586 Supplier Medchem Express Supplier No. HY19319

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Description

MedChemExpress MI-136 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors.

MI-136 is an inhibitor of the menin-MLL protein-protein interaction (PPI), with an IC50 of 31 nM and a Kd of 23.6 nM. MI-136 shows to block AR signaling and has the potential for the study in castration-resistant tumors.

Specifications

Chemical Name or Material MI-136
CAS 1628316-74-4
Color White
Purity Grade Notes Research
Molecular Formula C23H21F3N6S
Quantity 100 mg
Solubility Information DMSO : 110 mg/mL (233.79 mM; Need ultrasonic)
SMILES FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(NC(C#N)=C5)C5=C4)CC3
Molecular Weight (g/mol) 470.51
Formula Weight 470.51
Percent Purity 99.71%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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