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Invitrogen™ MICB Monoclonal Antibody (12)

Description
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human MICB/MIC-B.
MICB encodes the highly polymorphic MHC (HLA) class I chain-related gene B. The protein product is expressed on the cell surface. It is thought that MICB functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. MICB is broadly recognized by NK cells and T cells with NKG2D receptor on their surface. The complex NKG2D-MICB results in MICB expressing cytolytic T cells and NK cells against epithelial tumor cells.
Specifications
Specifications
| Antigen | MICB |
| Applications | ELISA, Flow Cytometry |
| Classification | Monoclonal |
| Clone | 12 |
| Concentration | 1.37 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with no preservative |
| Gene | MICB |
| Gene Accession No. | Q29980 |
| Gene Alias | MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence B; MHC class I-like located near the LRC, 2; MHC class I-like molecule PERB11.2-IMX; MHC I like leukocyte 2; MICB; MIC-B; Mill2; Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1; PERB11.2; sMICB; soluble MICB; stress inducible class I homolog |
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