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Invitrogen™ MICB Polyclonal Antibody
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Product Code. 16510082
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Quantity:
100 μL
Unit Size:
100µL
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16510082 100 μL 100µL
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Product Code. 16510082 Supplier Invitrogen™ Supplier No. PA597245

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AEPHSLRYNL MVLSQDGSVQ SGFLAEGHLD GQPFLRYDRQ KRRAKPQGQW AENVLGAKTW DTETEDLTEN GQDLRRTLTH IKDQKG; Positive Samples: NCI-H460, SKOV3; Cellular Location: Cell membrane, Single-pass type I membrane protein.

MICB encodes the highly polymorphic MHC (HLA) class I chain-related gene B. The protein product is expressed on the cell surface. It is thought that MICB functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. MICB is broadly recognized by NK cells and T cells with NKG2D receptor on their surface. The complex NKG2D-MICB results in MICB expressing cytolytic T cells and NK cells against epithelial tumor cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MICB
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.97 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MICB
Gene Accession No. Q29980
Gene Alias MHC class I chain-related protein B; MHC class I mic-B antigen; MHC class I polypeptide-related sequence B; MHC class I-like located near the LRC, 2; MHC class I-like molecule PERB11.2-IMX; MHC I like leukocyte 2; MICB; MIC-B; Mill2; Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1; PERB11.2; sMICB; soluble MICB; stress inducible class I homolog
Gene Symbols MICB
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 23-108 of human MICB (NP_0059222).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4277
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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