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Invitrogen™ MIER1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA554032
This item is not returnable.
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Description
Immunogen sequence: MMEGETNFSS EIEDLAREGD MPIHELLSLY GYGSTVRLPE EDEEEEEEEE EGEDDEDADN DDNSGCSGEN KEENIKDSSG QEDETQSSND DPSQSVASQD AQEI Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
Specifications
| MIER1 | |
| Polyclonal | |
| Unconjugated | |
| MIER1 | |
| 4933425I22Rik; 5830411K19Rik; early response 1; er1; hMI-ER1; Kiaa1610; mesoderm induction early response 1 homolog; mesoderm induction early response 1 homolog (Xenopus laevis; mesoderm induction early response 1, transcriptional regulator; mesoderm induction early response protein 1; MIER1; MI-ER1; MIER1 transcriptional regulator; RGD1562337; RP5-944N15.1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 57708 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.1 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q8N108 | |
| MIER1 | |
| Recombinant protein corresponding to Human MIER1. Recombinant protein control fragment (Product #RP-91706). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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