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Miransertib, MedChemExpress

Product Code. 16483807
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Product Code. 16483807 Supplier Medchem Express Supplier No. HY19719

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Description

MedChemExpress Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research. Miransertib is effective against Leishmania.

Miransertib (ARQ-092) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. Miransertib is also a potent the AKT1-E17K mutant protein inhibitor and has the potential for PI3K/AKT-driven tumors and Proteus syndrome research. Miransertib is effective against Leishmania.

Specifications

Chemical Name or Material Miransertib
CAS 1313881-70-7
Color Yellow
Purity Grade Notes Research
Molecular Formula C27H24N6
Quantity 50 mg
Synonym ARQ-092
Solubility Information DMSO : 12.5 mg/mL (28.90 mM; Need ultrasonic)
SMILES NC1=NC=CC=C1C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(C6(N)CCC6)C=C5
Molecular Weight (g/mol) 432.52
Formula Weight 432.52
Percent Purity 96.28%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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