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MK-4101, MedChemExpress

Product Code. 16499456
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Product Code. 16499456

missing translation for 'mfr': Medchem Express HY100036

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Description

MedChemExpress MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 μM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells; IC50 of 1 μM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis.

MK-4101 is a Smoothened (SMO) antagonist (IC50 of 1.1 μM for 293 cells ) and also a potent inhibitor of the hedgehog pathway (IC50 of 1.5 μM for mouse cells

Specifications

Chemical Name or Material MK-4101
Physical Form Solid
CAS 935273-79-3
Color White
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C24H24F5N5O
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 50 mg/mL (101.32 mM)
SMILES FC(C1=CC=CC=C1C2=NN=C(C34CCC(C5=NOC(C6CC(F)(F)C6)=N5)(CC4)CC3)N2C)(F)F
Molecular Weight (g/mol) 493.47
Formula Weight 493.47
Percent Purity 98.1%
Grade Research
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Research purposes only

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