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Invitrogen™ MKK7 Recombinant Rabbit Monoclonal Antibody (SD20-87)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA532362
This item is not returnable.
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Description
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.
Specifications
| MKK7 | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4 | |
| O14733, Q4KSH7, Q8CE90 | |
| MAP2K7 | |
| Synthetic peptide within Human MEK7 aa 370-419. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot | |
| SD20-87 | |
| Unconjugated | |
| MAP2K7 | |
| 2; 5930412N11Rik; c-Jun N-terminal kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 7; EMBL:AAX61178.1}; JN; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAP2K4; map2k7; map2k7 {ECO:0000312; MAPK/ERK kinase 4; MAPK/ERK kinase 7; MAPKK 4; MAPKK 7; MAPKK7; MEK; MEK 4; MEK 7; Mek7; mitogen activated protein kinase kinase 7; mitogen-activated protein kinase kinase 7; Mkk7; PRKMK7; protein kinase, mitogen activated, kinase 7; SAPK kinase 1; SAPK kinase 4; SAPK/ERK kinase 1; SAPKK1; SAPKK-1; SAPKK4; SAPKK-4; SEK1; sek2; SKK4; Stress-activated protein kinase kinase 4 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 26400, 363855, 5609 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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