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Invitrogen™ MKP2 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA566440

Product Code. 15919144

  • € 578.00 / 100µL

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Description

Description

Immunogen sequence: QVLATSCAAEA ASPSGPLRER GKTPATPTSQ FVFSFPVSVG VHSAPSSLPY LHS Highest antigen sequence identity to the following orthologs - mouse 89%, rat 89%.

DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MKP2
Polyclonal
Unconjugated
DUSP4
2700078F24Rik; AI844617; BB104621; dual specificity phosphatase 4; dual specificity protein phosphatase 4; Dual specificity protein phosphatase hVH2; DUSP 4; DUSP4; DUSP-4; E130306H24Rik; HVH2; MAP kinase phosphatase 2; mitogen-activated protein kinase phosphatase 2; MKP II; Mkp2; Mkp-2; MKPII; serine/threonine specific protein phosphatase; TYP; VH1 homologous phosphatase 2; VH2
Rabbit
Antigen affinity chromatography
RUO
1846
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q13115
DUSP4
Recombinant Human MKP2. Recombinant protein control fragment (Product #RP-107115).
100 μL
Primary
Human
Antibody
IgG
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