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Invitrogen™ MLH3 Recombinant Rabbit Monoclonal Antibody (6H7J5)

Rabbit Recombinant Monoclonal Antibody

Brand: Invitrogen™ MA555489

Product Code. 30131087

€ 436.00 / 100µL

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Description

Immunogen Sequence: QVLQQVDNKF IACLMSTKTE ENGEAGGNLL VLVDQHAAHE RIRLEQLIID SYEKQQAQGS GRKKLLSSTL IPPLEITVTE EQRRLLWCYH KNLEDLGLEF VFPDTSDSLV LVGKVPLCFV EREANELRRG RSTVTKSIVE EFIREQLELL QTTGGIQGTL PLTVQKVLAS QACHGAIKFN DGLSLQESCR LIEALSSCQL.

This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Specifications

Antigen	MLH3
Classification	Recombinant Monoclonal
Concentration	1.09 mg/mL
Formulation	PBS with 50% glycerol, 0.05% BSA and 0.09% sodium azide, pH 7.3
Gene Accession No.	Q9UHC1
Gene Symbols	MLH3
Immunogen	Recombinant protein (or fragment)
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human, Mouse
Product Type	Antibody
Isotype	IgG

Applications	ELISA, Western Blot
Clone	6H7J5
Conjugate	Unconjugated
Gene	MLH3
Gene Alias	AV125803; BB126472; CAE; CAE1; cell surface glycoprotein; connexin 50; connexin-50; CTRCT1; CX50; CZP1; DNA mismatch repair protein Mlh3; gap junction alpha 8; gap junction alpha-8 protein; gap junction membrane channel protein alpha-8; gap junction protein alpha 8; gap junction protein alpha 8 50kDa; GJA8; HNPCC7; lens fiber protein MP70; lens intrinsic membrane protein MP70; MGC138372; MLH3; MP70; mutL homolog 3; mutL homolog 3 (E coli); MutL protein homolog 3
Host Species	Rabbit
Purification Method	Protein A
Regulatory Status	RUO
Gene ID (Entrez)	217716, 27030
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

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Invitrogen™ MLH3 Recombinant Rabbit Monoclonal Antibody (6H7J5)

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