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Invitrogen™ MLK3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5106260
This item is not returnable.
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Description
Antibody detects endogenous levels of total MLK3.
MAP3K11 (MLK3) is a serine/threonine kinase that activates both the p38 MAP kinase and c-Jun kinase pathways. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
Specifications
| MLK3 | |
| Polyclonal | |
| Unconjugated | |
| MAP3K11 | |
| 2610017K16Rik; MAP3K11; MEKK11; MGC17114; mitogen activated protein kinase kinase kinase 11; mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Mlk3; MLK-3; protein-tyrosine kinase PTK1; PTK1; RHOE; SH3 domain-containing proline-rich kinase; SPRK; Src-homology 3 domain-containing proline-rich kinase | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 26403, 309168, 4296 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q16584, Q66HA1, Q80XI6 | |
| MAP3K11 | |
| A synthesized peptide derived from human MAP3K11(Accession Q16584), corresponding to amino acid residues T649-S699. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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