Learn More
ADRBK1, Mouse, Clone: 5D5, Abnova™
Description
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq
Specifications
Specifications
| Antigen | ADRBK1 |
| Applications | Immunocytochemistry, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 5D5 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant ADRBK1. |
| Dilution | Immunohistochemistry (1:100) Western Blot (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In tissue culture supernatant |
| Gene | ADRBK1 |
| Gene Alias | BARK1/BETA-ARK1/FLJ16718/GRK2 |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.