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CA9, Mouse, Clone: SPM314, Abnova™
Mouse monoclonal antibody raised against CA9.
Brand: Abnova MAB12024.100ug
This item is not returnable.
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Description
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq
Specifications
| CA9 | |
| Monoclonal | |
| Unconjugated | |
| Immunohistochemistry (0.5-1 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. | |
| CA9 | |
| CA9 | |
| Microsomal fraction of human renal cortical tissue homogenate. | |
| 100 μg | |
| Primary | |
| Human | |
| Liquid |
| Immunohistochemistry (PFA fixed), Western Blot | |
| SPM314 | |
| Mouse monoclonal antibody raised against CA9. | |
| In 10mM PBS (0.05% BSA, 0.05% sodium azide) | |
| CAIX/MN | |
| Mouse | |
| Protein A/G purification | |
| RUO | |
| 768 | |
| Store at 4°C. Aliquot to avoid repeated freezing and thawing. |
|
| IgG2b κ |
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