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CAV1, Mouse, Clone: 4D6, Abnova™

Product Code. 16025986
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1 mL
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Product Code. 16025986 Supplier Abnova Supplier No. MAB3768.1mL

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Mouse monoclonal antibody raised against partial recombinant CAV1.

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq

Specifications

Antigen CAV1
Applications Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 4D6
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant CAV1.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Western Blot (1:4000) The optimal working dilution should be determined by the end user.
Formulation In tissue culture supernatant (0.09% sodium azide)
Gene CAV1
Gene Alias BSCL3/CAV/CGL3/MSTP085/VIP21
Gene Symbols CAV1
Host Species Mouse
Immunogen Recombinant protein corresponding to N-terminus of human CAV1.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 857
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG2a κ
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