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CD180, Mouse, PE, Clone: G28-8, Abnova™
Mouse monoclonal antibody raised against of CD180.
Brand: Abnova MAB10239.100Reactions
Description
CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. [provided by RefSeq
Specifications
| CD180 | |
| Monoclonal | |
| PE | |
| Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells) The optimal working dilution should be determined by the end user. | |
| CD180 | |
| CD180 | |
| Human tonsillar B cells. | |
| 100 Reactions | |
| Primary | |
| CD180, a TLR-like glycoprotein expressed on peripheral blood monocytes and dendritic cells, mantle zone B cells and marginal zone B cells, but very weakly on germinal center B cells. | |
| Store at 4°C. Do not freeze. | |
| IgG1 |
| Flow Cytometry, Functional Assay, Immunoprecipitation | |
| G28-8 | |
| Mouse monoclonal antibody raised against of CD180. | |
| In PBS (0.2% BSA, 0.09% sodium azide) | |
| LY64/Ly78/MGC126233/MGC126234/RP105 | |
| Mouse | |
| Size-exclusion chromatography purification | |
| RUO | |
| 4064 | |
| Human | |
| Liquid |
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