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  6. 16036406

CD45RB, Mouse, FITC, Clone: MEM-55, Abnova™

Mouse monoclonal antibody raised against native CD45RB.

Brand:  Abnova MAB4631.100Reactions

Product Code. 16036406

  • € 388.00 / 100 reactions

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Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq

Specifications

Specifications

CD45RB
Monoclonal
FITC
Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user.
PTPRC
PTPRC
Native purified CD45RB from human thymocytes and T lymphocytes.
RUO
5788
Human, Non-human Primate
Liquid
Flow Cytometry
MEM-55
Mouse monoclonal antibody raised against native CD45RB.
In PBS (0.2% BSA, 0.09% sodium azide)
B220/CD45/CD45R/GP180/LCA/LY5/T200
Mouse
100 Reactions
Primary
This antibody recognizes a siliadase-sensitive epitope of CD45RB, a 180-240 KDa single chain type I membrane glycoprotein, variant of CD45 (CD45RB isoform).
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
IgG1
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