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CD63, Mouse, PE, Clone: MEM-259, Abnova™
Mouse monoclonal antibody raised against native CD63.
Brand: Abnova MAB4458.100Reactions
Description
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq
Specifications
| CD63 | |
| Monoclonal | |
| PE | |
| Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. | |
| CD63 | |
| CD63 | |
| Native purified CD63 from human T cell line HPB-ALL. | |
| RUO | |
| 967 | |
| Human | |
| Liquid |
| Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot | |
| MEM-259 | |
| Mouse monoclonal antibody raised against native CD63. | |
| In PBS (0.2% BSA, 0.09% sodium azide) | |
| LAMP-3/ME491/MLA1/OMA81H/TSPAN30 | |
| Mouse | |
| 100 Reactions | |
| Primary | |
| This antibody reacts with CD63 (LAMP-3), a 40-60 KDa tetraspan glycoprotein expressed by granulocytes, platelets, T cells, monocytes/macrophages and endothelial cells. Cell surface exposition of CD63 is usually activation-dependent. | |
| Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
|
| IgG1 |
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