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DUX4, Mouse, ATTO488, Clone: P2B1, Abnova™
Mouse monoclonal antibody raised against recombinant partial DUX4.
Brand: Abnova MAB11444.100ug
This item is not returnable.
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Description
This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that contains two homeoboxes; the repeat-array and ORF is conserved in other mammals. There was no evidence for transcription from standard cDNA libraries however RTPCR and in-vitro expression experiments indicate that the ORF is transcribed and the encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the microsatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq
Specifications
| DUX4 | |
| Monoclonal | |
| Atto 488 | |
| Western Blot (1:1000) The optimal working dilution should be determined by the end user. | |
| DUX4 | |
| DUX4 | |
| Recombinant GST fusion protein corresponding to a 76 amino acid fragment at C-terminus of human DUX4. | |
| 100 μg | |
| Primary | |
| This antibody recognizes human DUX4. It does not cross-react with DUX4c. | |
| Store at 4°C. Aliquot to avoid repeated freezing and thawing. |
|
| IgG1 |
| Immunofluorescence, Immunohistochemistry, Western Blot | |
| P2B1 | |
| Mouse monoclonal antibody raised against recombinant partial DUX4. | |
| In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide) | |
| DUX10 | |
| Mouse | |
| Protein G purification | |
| RUO | |
| 22947 | |
| Human | |
| Liquid |
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