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EPHB4, Mouse, Clone: 7H4A6, Abnova™
Description
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq
Specifications
Specifications
| Antigen | EPHB4 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 7H4A6 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant EPHB4. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | EPHB4 |
| Gene Alias | HTK/MYK1/TYRO11 |
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