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HSPA5, Mouse, Monoclonal Antibody, Abnova™
Description
When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM
Specifications
Specifications
| Antigen | HSPA5 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant HSPA5. |
| Dilution | Western Blot (1:100-1:2000) ELISA (1:5000-1:20000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol) |
| Gene | HSPA5 |
| Gene Alias | BIP/FLJ26106/GRP78/MIF2 |
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