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KRT8, Mouse, Clone: 8A5D12, Abnova™
Description
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. [provided by RefSeq
Specifications
Specifications
| Antigen | KRT8 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 8A5D12 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant KRT8. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | KRT8 |
| Gene Alias | CARD2/CK8/CYK8/K2C8/K8/KO |
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