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MMP3, Mouse, Clone: 1B4, Abnova™
Description
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
Specifications
Specifications
| Antigen | MMP3 |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 1B4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against synthetic peptide of MMP3. |
| Dilution | Western blot (1 to 2 ug/mL) Immunohistochemistry on formalin to fixed/paraffin to embedded tissues (1 to 5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.08% sodium azide) |
| Gene | MMP3 |
| Gene Alias | CHDS6/MGC126102/MGC126103/MGC126104/MMP-3/SL-1/STMY/STMY1/STR1 |
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