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MS4A2, Mouse, Polyclonal Antibody, Abnova™
Description
The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. This gene encodes the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member is localized to 11q12, among a cluster of family members. Alternative splicing results in multiple transcript variants encoding different isoforms
Specifications
Specifications
| Antigen | MS4A2 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant MS4A2. |
| Formulation | 50% glycerol |
| Gene | MS4A2 |
| Gene Accession No. | NM_000139 |
| Gene Alias | APY/ATOPY/FCER1B/FCERI/IGEL/IGER/IGHER/MS4A1 |
| Gene Symbols | MS4A2 |
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