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  6. 16070786

PTPRC, Mouse, Clone: PD7-26, Abnova™

mouse monoclonal antibody raised against PTPRC.

Brand:  Abnova MAB11484.100ug

Product Code. 16070786

  • € 503.00 / 100µg

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Description

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq

Specifications

Specifications

PTPRC
Monoclonal
Unconjugated
Flow Cytometry (0.5-1 ug/million cells) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (0.5-1 ug/mL for 30 min at RT) Immunoprecipitation (0.5-1 ug/500 ug protein lysate) Western Blot (0.5-1 ug/mL) The optimal working dilution should
PTPRC
PTPRC
Human peripheral blood lymphocytes maintained in T cell growth factor.
100 μg
Primary
Human
Liquid
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
PD7-26
mouse monoclonal antibody raised against PTPRC.
In PBS (0.05% BSA, 0.05% sodium azide)
B220/CD45/CD45R/GP180/LCA/LY5/T200
Mouse
Protein A/G affinity chromatography
RUO
5788
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
IgG1 κ
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